The Mechanism of Resistance to Sulfonamides
نویسندگان
چکیده
منابع مشابه
Resistance to trimethoprim and sulfonamides.
Sulfonamides and trimethoprim have been used for many decades as efficient and inexpensive antibacterial agents for animals and man. Resistance to both has, however, spread extensively and rapidly. This is mainly due to the horizontal spread of resistance genes, expressing drug-insensitive variants of the target enzymes dihydropteroate synthase and dihydrofolate reductase, for sulfonamide and t...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1944
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.48.6.631-638.1944